Anti-z DNA抗体(ab2079)
Key features and details
- Sheep polyclonal to z DNA
- Suitable for: IP, In situ hybridization
- Reacts with: Species independent
- Isotype: IgG
概述
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产品名称
Anti-z DNA抗体 -
描述
羊多克隆抗体to z DNA -
宿主
Sheep -
经测试应用
适用于: IP, In situ hybridizationmore details -
种属反应性
与反应: Species independent -
免疫原
Z-DNA
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.50
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Isotype control
应用
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab2079 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用 | Ab评论 | 说明 |
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IP |
Use at an assay dependent dilution.
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In situ hybridization |
Use at an assay dependent dilution. See below; Cerna, A. et al, European journal of Histochemistry.
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说明 |
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IP
Use at an assay dependent dilution. |
In situ hybridization
Use at an assay dependent dilution. See below; Cerna, A. et al, European journal of Histochemistry. |
靶标
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相关性
Z-DNA is one of the many possible double helical structures of DNA. It is a left-handed double helical structure in which the double helix winds to the left in a zig-zag pattern (instead of to the right, like the more common B-DNA form). Z-DNA is thought to be one of three biologically active double helical structures along with A- and B-DNA.
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab2079 被引用在 4 文献中.
- Leonova K et al. TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells. Elife 7:N/A (2018). PubMed: 29400649
- Safina A et al. FACT is a sensor of DNA torsional stress in eukaryotic cells. Nucleic Acids Res 45:1925-1945 (2017). PubMed: 28082391
- Lu P et al. The Za domain of fish PKZ converts DNA hairpin with d(GC)n inserts to Z-conformation. Acta Biochim Biophys Sin (Shanghai) 45:1062-8 (2013). PubMed: 24113090
- Cerná A et al. Z-DNA, a new in situ marker for transcription. Eur J Histochem 48:49-56 (2004). PubMed: 15145775