Anti-VEGFB抗体(ab185696)
Key features and details
- Rabbit polyclonal to VEGFB
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-VEGFB抗体
参阅全部 VEGFB 一抗 -
描述
兔多克隆抗体to VEGFB -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse
预测可用于: Cow, Human -
免疫原
Recombinant fragment corresponding to Human VEGFB aa 1 to the C-terminus.
Database link: P49765 -
阳性对照
- WB: Mouse heart tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab185696于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/2000. Predicted molecular weight: 22 kDa.
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说明 |
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WB
1/500 - 1/2000. Predicted molecular weight: 22 kDa. |
靶标
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功能
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. -
组织特异性
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. -
序列相似性
Belongs to the PDGF/VEGF growth factor family. -
翻译后修饰
VEGF-B186 is O-glycosylated. -
细胞定位
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. - Information by UniProt
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数据库链接
- Entrez Gene: 7423 Human
- Entrez Gene: 22340 Mouse
- Omim: 601398 Human
- SwissProt: P49765 Human
- SwissProt: P49766 Mouse
- Unigene: 78781 Human
- Unigene: 15607 Mouse
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形式
There are 2 isoforms produced by alternative splicing. -
别名
- Vascular endothelial growth factor B antibody
- Vascular endothelial growth factor-related factor antibody
- VEGF B antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (7)
ab185696 被引用在 7 文献中.
- Yen JH et al. Improved Wound Healing by Naringin Associated with MMP and the VEGF Pathway. Molecules 27:N/A (2022). PubMed: 35268795
- Zhang Y et al. Effect of intravitreal conbercept injection on VEGF-A and -B levels in the aqueous and vitreous humor of patients with proliferative diabetic retinopathy. Exp Ther Med 21:332 (2021). PubMed: 33732305
- Zhu X et al. Class A1 scavenger receptor prevents obesity-associated blood pressure elevation through suppressing overproduction of vascular endothelial growth factor B in macrophages. Cardiovasc Res 117:547-560 (2021). PubMed: 32044963
- Wang H et al. Pigment Epithelial-Derived Factor Deficiency Accelerates Atherosclerosis Development via Promoting Endothelial Fatty Acid Uptake in Mice With Hyperlipidemia. J Am Heart Assoc 8:e013028 (2019). PubMed: 31711388
- Rothhammer V et al. Microglial control of astrocytes in response to microbial metabolites. Nature 557:724-728 (2018). PubMed: 29769726
- Lv YX et al. VEGF-A and VEGF-B Coordinate the Arteriogenesis to Repair the Infarcted Heart with Vagus Nerve Stimulation. Cell Physiol Biochem 48:433-449 (2018). PubMed: 30016789
- Lu B et al. Effect of CCL2 siRNA on proliferation and apoptosis in the U251 human glioma cell line. Mol Med Rep 16:3387-3394 (2017). PubMed: 28714025