存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
纯度Immunogen affinity purified
Our Abpromise guarantee covers the use of ab180643 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 34 kDa.|
|IHC-P||1/50 - 1/200.|
|ICC/IF||Use at an assay dependent concentration.|
功能UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
组织特异性Only in skeletal muscle and heart. Is more expressed in glycolytic than in oxidative skeletal muscles.
疾病相关Defects in UCP3 may be involved in obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
序列相似性Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
细胞定位Mitochondrion inner membrane.
- Information by UniProt
形式UCP3 is preferentially expressed in muscle
- Mitochondrial uncoupling protein 3 antibody
- SLC25A9 antibody
- Solute carrier family 25 member 9 antibody
Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab180643. Blue DAPI for nuclear staining.
All lanes : Anti-UCP3 antibody (ab180643) at 1/500 dilution
Lane 1 : mouse testis cell line extract
Lane 2 : mouse liver cell line extract
Lane 3 : mouse lung cell line extract
Predicted band size: 34 kDa
ab180643 has not yet been referenced specifically in any publications.