Anti-UCP2抗体(ab203244)
Key features and details
- Rabbit polyclonal to UCP2
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-UCP2抗体
参阅全部 UCP2 一抗 -
描述
兔多克隆抗体to UCP2 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide within Mouse UCP2 aa 200-300 conjugated to keyhole limpet haemocyanin. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: P70406 -
阳性对照
- Mouse brain tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA, 48.98% TBS, 1X
Aqueous buffered solution -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab203244于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P | (1) |
1/100 - 1/500.
(or 1/50 - 1/200 if using a fluorescent secondary antibody) |
说明 |
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IHC-P
1/100 - 1/500. (or 1/50 - 1/200 if using a fluorescent secondary antibody) |
靶标
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功能
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. -
组织特异性
Widely expressed in adult human tissues, including tissues rich in macrophages. Most expressed in white adipose tissue and skeletal muscle. -
序列相似性
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats. -
细胞定位
Mitochondrion inner membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 22228 Mouse
- SwissProt: P70406 Mouse
- Unigene: 171378 Mouse
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别名
- BMIQ4 antibody
- Mitochondrial uncoupling protein 2 antibody
- SLC25A8 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (13)
ab203244 被引用在 13 文献中.
- Yeh CC et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep 25:N/A (2022). PubMed: 34913071
- Yu X et al. Identification of UCP1 and UCP2 as Potential Prognostic Markers in Breast Cancer: A Study Based on Immunohistochemical Analysis and Bioinformatics. Front Cell Dev Biol 10:891731 (2022). PubMed: 35874806
- Wang CH et al. Losartan Prevents Hepatic Steatosis and Macrophage Polarization by Inhibiting HIF-1α in a Murine Model of NAFLD. Int J Mol Sci 22:N/A (2021). PubMed: 34360607
- Bi J et al. Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin aVß5 receptor. J Cell Mol Med 24:996-1009 (2020). PubMed: 31701659
- Bartolome F et al. Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge. J Neuroinflammation 17:22 (2020). PubMed: 31937343