Anti-CIP75抗体(ab106443)
Key features and details
- Rabbit polyclonal to CIP75
- Suitable for: IHC-P, WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-CIP75抗体
参阅全部 CIP75 一抗 -
描述
兔多克隆抗体to CIP75 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide corresponding to Human CIP75 (N terminal).
Database link: Q9NRR5 -
阳性对照
- 3T3 cell lysate, Mouse kidney tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106443于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
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WB | (1) |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 64 kDa.
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说明 |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 64 kDa. |
靶标
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组织特异性
Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver. -
序列相似性
Contains 1 UBA domain.
Contains 1 ubiquitin-like domain. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus. Cytoplasm. Endoplasmic reticulum. May associate with the endoplasmic reticulum. - Information by UniProt
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数据库链接
- Entrez Gene: 94232 Mouse
- SwissProt: Q99NB8 Mouse
- Unigene: 303059 Mouse
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别名
- 28S ribosomal protein S7 antibody
- A1U antibody
- A1Up antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab106443 被引用在 4 文献中.
- Liu F et al. UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma. Mol Oncol 15:3738-3752 (2021). PubMed: 34245648
- Sentürk M et al. Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Nat Cell Biol 21:384-396 (2019). PubMed: 30804504
- Itakura E et al. Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. Mol Cell 63:21-33 (2016). WB ; Human . PubMed: 27345149
- Coffey RT et al. Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling. J Biol Chem 291:5221-33 (2016). PubMed: 26740621