Anti-TSLP抗体(ab115700)
Key features and details
- Rabbit polyclonal to TSLP
- Suitable for: ELISA, WB, IHC-P
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-TSLP抗体
参阅全部 TSLP 一抗 -
描述
兔多克隆抗体to TSLP -
宿主
Rabbit -
经测试应用
适用于: ELISA, WB, IHC-Pmore details -
种属反应性
与反应: Mouse
预测可用于: Rat -
免疫原
Synthetic peptide corresponding to Mouse TSLP aa 70-120 (internal sequence) conjugated to keyhole limpet haemocyanin.
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阳性对照
- Mouse Liver and Spleen tissues; A20 cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab115700于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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WB |
Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 18 kDa.
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IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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ELISA
Use at an assay dependent concentration. |
WB
Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 18 kDa. |
IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Cytokine that induces the release of T cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. -
组织特异性
Expressed in a number of tissues including heart, liver and prostate. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 53603 Mouse
- Entrez Gene: 688621 Rat
- SwissProt: Q9JIE6 Mouse
- Unigene: 143716 Mouse
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别名
- Thymic stromal lymphopoietin antibody
- Thymic stromal lymphopoietin protein TSLP antibody
- Tslp antibody
see all
图片
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ab115700, at 5 µg/ml, staining TSLP in Formalin-fixed, Paraffin-embedded Mouse Liver tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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ab115700, at 5 µg/ml, staining TSLP in Formalin-fixed, Paraffin-embedded Mouse Spleen tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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Lane 1 : Anti-TSLP antibody (ab115700) at 0.5 µg/ml
Lane 2 : Anti-TSLP antibody (ab115700) at 1 µg/ml
Lane 3 : Anti-TSLP antibody (ab115700) at 2 µg/ml
All lanes : A20 cell lysate
Predicted band size: 18 kDa
数据表及文件
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Datasheet download
文献 (7)
ab115700 被引用在 7 文献中.
- Chun J et al. Modulation of the Gut Microbiota by Sihocheonggan-Tang Shapes the Immune Responses of Atopic Dermatitis. Front Pharmacol 12:722730 (2021). PubMed: 34616298
- Kim HJ et al. Protease-Activated Receptors 2-Antagonist Suppresses Asthma by Inhibiting Reactive Oxygen Species-Thymic Stromal Lymphopoietin Inflammation and Epithelial Tight Junction Degradation. Allergy Asthma Immunol Res 11:560-571 (2019). PubMed: 31172724
- Verma M et al. Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations. J Allergy Clin Immunol 142:793-803.e8 (2018). PubMed: 29132961
- Guo JZ et al. The role of metallothionein in a dinitrofluorobenzene-induced atopic dermatitis-like murine model. Sci Rep 8:11129 (2018). PubMed: 30042397
- Wang Y et al. Role of thymic stromal lymphopoietin in the pathogenesis of lumbar disc degeneration. Medicine (Baltimore) 96:e7516 (2017). ICC/IF ; Human . PubMed: 28746197
- Wu C et al. TSLPR deficiency attenuates atherosclerotic lesion development associated with the inhibition of TH17 cells and the promotion of regulator T cells in ApoE-deficient mice. J Mol Cell Cardiol 76C:33-45 (2014). Mouse . PubMed: 25117469
- Rebane A et al. MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes. J Allergy Clin Immunol 134:836-847.e11 (2014). PubMed: 24996260