Trolox,Antioxidant vitamin E derivative (ab120747)
Key features and details
- Antioxidant vitamin E derivative
- CAS Number: 53188-07-1
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Trolox,Antioxidant vitamin E derivative -
描述
Antioxidant vitamin E derivative -
生物学描述
Antioxidant vitamin E derivative. Exhibits lipid peroxidizing, DPPH° scavenging and HO° scavenging activity. Regularly used as an antioxidant standard. Cell-permeable and water soluble.
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纯度
> 98% -
CAS编号
53188-07-1 -
化学结构
性能
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化学名称
3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid -
分子量
250.29 -
分子式
C14H18O4 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
- Biochemicals
- Pharmacology
- Signaling
- Signal transduction
- Nitric oxide & oxidative stress
- Antioxidants
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Signal transduction
- Nitric oxide signaling
- Antioxidants
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Signal transduction
- Nitric oxide signaling
- Antioxidants
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Signal transduction
- Nitric oxide signaling
- Antioxidants
图片
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2D chemical structure image of ab120747, Trolox, Antioxidant vitamin E derivative
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Endothelial cells were cocultured with Nef-transfected Jurkat cells for 24 h, and then treated with apocynin (200 nM), trolox (200 nM), Nox2 inhibitor (1 µM) or IKKi (100 nM) and incubated an additional 18 h, then analyzed for Nef-induced MCP-1 production (C) and apoptosis of endothelial cells (D). Data were expressed as fold MCP-1 production and apoptosis, normalized to the mean of control measurements.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (2)
ab120747 被引用在 2 文献中.
- Liu P et al. Mammalian mitochondrial RNAs are degraded in the mitochondrial intermembrane space by RNASET2. Protein Cell 8:735-749 (2017). PubMed: 28730546
- Wang T et al. Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction. PLoS One 9:e91063 (2014). PubMed: 24608713