Anti-TRIM46抗体(ab169044)
Key features and details
- Mouse polyclonal to TRIM46
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TRIM46抗体
参阅全部 TRIM46 一抗 -
描述
小鼠多克隆抗体to TRIM46 -
宿主
Mouse -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Recombinant full length protein within Human TRIM46 aa 1-500. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- TRIM46 transfected 293T cell lysate; HepG2 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab169044于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa.
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ICC/IF |
Use a concentration of 20 µg/ml.
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说明 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa. |
ICC/IF
Use a concentration of 20 µg/ml. |
靶标
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序列相似性
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 COS domain.
Contains 1 fibronectin type-III domain.
Contains 2 RING-type zinc fingers. - Information by UniProt
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数据库链接
- Entrez Gene: 80128 Human
- Entrez Gene: 360213 Mouse
- Omim: 600986 Human
- SwissProt: Q7Z4K8 Human
- SwissProt: Q7TNM2 Mouse
- Unigene: 287735 Human
- Unigene: 331156 Mouse
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别名
- fibronectin type-III and C-terminal SPRY motif protein antibody
- Gene Y protein antibody
- GeneY antibody
see all
图片
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All lanes : Anti-TRIM46 antibody (ab169044) at 1 µg/ml
Lane 1 : TRIM46 transfected 293T cell lysate
Lane 2 : non transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat anti-mouse HRP conjugated antibody at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 55 kDa -
Immunofluorescent analysis of HepG2 cells labeling TRIM46 with ab169044 at 20 µg/ml.
实验方案
数据表及文件
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Datasheet download
文献 (2)
ab169044 被引用在 2 文献中.
- Tantai J et al. TRIM46 activates AKT/HK2 signaling by modifying PHLPP2 ubiquitylation to promote glycolysis and chemoresistance of lung cancer cells. Cell Death Dis 13:285 (2022). PubMed: 35354796
- Li Y et al. Clostridium difficile toxin B induces colonic inflammation through the TRIM46/DUSP1/MAPKs and NF-?B signalling pathway. Artif Cells Nanomed Biotechnol 48:452-462 (2020). PubMed: 31918570