PE Anti-TRAIL抗体[N2B2] (ab95532)
Key features and details
- PE Rat monoclonal [N2B2] to TRAIL
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
概述
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产品名称
PE Anti-TRAIL抗体[N2B2]
参阅全部 TRAIL 一抗 -
描述
PE大鼠单克隆抗体[N2B2] to TRAIL -
宿主
Rat -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse TRAIL. Mouse TRAIL-transfected 2PK-3 cells.
Database link: P50592 -
阳性对照
- Flow Cyt: Mouse TRAIL transfected cells.
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常规说明
ab95532 inhibits IL-2 or IL-15 activated NK cell cytotoxicity against mouse fibrosarcoma L929 target cells.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
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纯度
Protein G purified -
Primary antibody说明
ab95532 inhibits IL-2 or IL-15 activated NK cell cytotoxicity against mouse fibrosarcoma L929 target cells. -
克隆
单克隆 -
克隆编号
N2B2 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95532于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use 0.06-0.125µg for 105-8 cells.
Staining the cell sample in a final volume of 100µl is recommended.
ab134674 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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说明 |
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Flow Cyt
Use 0.06-0.125µg for 105-8 cells. Staining the cell sample in a final volume of 100µl is recommended.
ab134674 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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靶标
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功能
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. -
组织特异性
Widespread; most predominant in spleen, lung and prostate. -
序列相似性
Belongs to the tumor necrosis factor family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 22035 Mouse
- SwissProt: P50592 Mouse
- Unigene: 1062 Mouse
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别名
- Apo 2 ligand antibody
- APO 2L antibody
- Apo-2 ligand antibody
see all
图片
数据表及文件
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Datasheet download
文献 (3)
ab95532 被引用在 3 文献中.
- Taieb J et al. A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med 12:214-9 (2006). PubMed: 16444265
- Hayakawa Y et al. NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy. J Immunol 172:123-9 (2004). PubMed: 14688317
- Kayagaki N et al. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells. J Immunol 163:1906-13 (1999). PubMed: 10438925