Anti-TOM70抗体(ab89624)
Key features and details
- Mouse polyclonal to TOM70
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TOM70抗体
参阅全部 TOM70 一抗 -
描述
小鼠多克隆抗体to TOM70 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human TOM70. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. (NP_055635).
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阳性对照
- Human liver tissue lysate, HepG2 whole cell lysate (ab7900) and TOM70 transfected 293T cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab89624于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 67 kDa.
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说明 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 67 kDa. |
靶标
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功能
Receptor that accelerates the import of all mitochondrial precursor proteins. -
序列相似性
Belongs to the Tom70 family.
Contains 10 TPR repeats. -
细胞定位
Mitochondrion outer membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 9868 Human
- Omim: 606081 Human
- SwissProt: O94826 Human
- Unigene: 227253 Human
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别名
- FLJ9047 antibody
- Mitochondrial import receptor subunit TOM70 antibody
- Mitochondrial precursor proteins import receptor antibody
see all
图片
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Anti-TOM70 antibody (ab89624) at 1 µg/ml + human liver tissue lysate at 50 µg
Predicted band size: 67 kDa
Observed band size: 67 kDa -
Anti-TOM70 antibody (ab89624) at 1 µg/ml + HepG2 cell lysate at 50 µg
Predicted band size: 67 kDa
Observed band size: 75 kDa why is the actual band size different from the predicted? -
All lanes : Anti-TOM70 antibody (ab89624) at 1 µg/ml
Lane 1 : TOMM70A transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 67 kDa
Observed band size: 75 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (4)
ab89624 被引用在 4 文献中.
- Richter M et al. The Recombinant Fragment of Human ?-Casein Induces Cell Death by Targeting the Proteins of Mitochondrial Import in Breast Cancer Cells. Cancers (Basel) 12:N/A (2020). PubMed: 32486420
- Reyes A et al. RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases. PLoS Genet 16:e1008923 (2020). PubMed: 32735630
- Wohlfromm F et al. Interplay Between Mitophagy and Apoptosis Defines a Cell Fate Upon Co-treatment of Breast Cancer Cells With a Recombinant Fragment of Human ?-Casein and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand. Front Cell Dev Biol 8:617762 (2020). PubMed: 33537307
- Rakovic A et al. Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons. J Biol Chem 288:2223-37 (2013). WB ; Human . PubMed: 23212910