Anti-TNFRSF14/HVEM抗体(ab62462)
Key features and details
- Rabbit polyclonal to TNFRSF14/HVEM
- Suitable for: WB, ICC
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TNFRSF14/HVEM抗体
参阅全部 TNFRSF14/HVEM 一抗 -
描述
兔多克隆抗体to TNFRSF14/HVEM -
宿主
Rabbit -
经测试应用
适用于: WB, ICCmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human TNFRSF14/HVEM (C terminal).
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阳性对照
- Raji cell lysate. Raji cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab62462于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 31 kDa).
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ICC |
Use a concentration of 10 - 20 µg/ml.
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说明 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 31 kDa). |
ICC
Use a concentration of 10 - 20 µg/ml. |
靶标
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功能
Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. -
组织特异性
Widely expressed, with the highest expression in lung, spleen and thymus. -
序列相似性
Contains 3 TNFR-Cys repeats. -
翻译后修饰
N-glycosylated. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 8764 Human
- Omim: 602746 Human
- SwissProt: Q92956 Human
- Unigene: 512898 Human
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别名
- HVEML antibody
- ATAR antibody
- CD270 antibody
see all
图片
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All lanes : Anti-TNFRSF14/HVEM antibody (ab62462) at 2 µg/ml
Lane 1 : Raji cell lysate with no blocking peptide
Lane 2 : Raji cell lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 31 kDa
Observed band size: 27 kDa why is the actual band size different from the predicted? -
Immunocytochemistry of TNFRSF14/HVEM in Raji cells with ab62462 antibody at 10 µg/ml.
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Immunofluorescence of TNFRSF14/HVEM in Raji cells using ab62462 at 20 ug/ml.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab62462 被引用在 1 文献中.
- Duan L et al. HVEM/HIF-1a promoted proliferation and inhibited apoptosis of ovarian cancer cells under hypoxic microenvironment conditions. J Ovarian Res 13:40 (2020). PubMed: 32312328