Anti-TIE1抗体(ab64477)
Key features and details
- Rabbit polyclonal to TIE1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TIE1抗体
参阅全部 TIE1 一抗 -
描述
兔多克隆抗体to TIE1 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human TIE1 aa 550-650 (C terminal). The exact sequence is proprietary.
Database link: P35590 -
阳性对照
- Human tonsil tissue
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常规说明
Cell membrane staining pattern
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab64477于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P | (1) |
1/100.
1/100 for 30 min at room temperature. |
说明 |
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IHC-P
1/100. 1/100 for 30 min at room temperature. |
靶标
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功能
Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. -
组织特异性
Specifically expressed in developing vascular endothelial cells. -
序列相似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.
Contains 3 EGF-like domains.
Contains 3 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
翻译后修饰
Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 7075 Human
- Omim: 600222 Human
- SwissProt: P35590 Human
- Unigene: 78824 Human
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别名
- JKT 14 antibody
- JTK14 antibody
- TIE antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab64477 被引用在 2 文献中.
- Sopo M et al. High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer. PLoS One 15:e0241484 (2020). PubMed: 33151982
- Allerkamp H et al. Characterization of a Porcine Model for Von Willebrand Disease Type 1 and 3 Regarding Expression of Angiogenic Mediators in the Nonpregnant Female Reproductive Tract. Comp Med 69:401-412 (2019). PubMed: 31526432