Anti-Tcl1抗体[1-21] (ab91211)
Key features and details
- Mouse monoclonal [1-21] to Tcl1
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG2b
Related conjugates and formulations
概述
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产品名称
Anti-Tcl1抗体[1-21]
参阅全部 Tcl1 一抗 -
描述
小鼠单克隆抗体[1-21] to Tcl1 -
宿主
Mouse -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide (Human)
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阳性对照
- Daudi cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
1-21 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab91211于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
说明 |
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IHC-P: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 13 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. -
组织特异性
Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation. -
疾病相关
Note=Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor alpha/delta loci. -
序列相似性
Belongs to the TCL1 family. -
细胞定位
Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Microsomal fraction. - Information by UniProt
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数据库链接
- Entrez Gene: 8115 Human
- Omim: 186960 Human
- SwissProt: P56279 Human
- Unigene: 2484 Human
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别名
- Anti TCL1A antibody
- Lymphoma/leukemia, T-cell antibody
- Oncogene TCL-1 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (0)
ab91211 尚未被引用在任何文献中。