Serpinb5
Function
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity (By similarity).
Sequence Similarities
Belongs to the serpin family. Ov-serpin subfamily.
Cellular localization
- Secreted
- Extracellular space
Alternative names
Pi5, Spi5, Spi7, Serpinb5, Serpin B5, Maspin, Peptidase inhibitor 5, PI-5