SEPTIN10
Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Post-translational modifications
Proteolytically cleaved in vitro in a calmodulin-dependent manner.
Sequence Similarities
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Tissue Specificity
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.
Cellular localization
- Cytoplasm
- Cytoplasm
- Cytoskeleton
- Cell projection
- Cilium
- Flagellum
- Detected in the annulus of the sperm flagellum and in the neck region in spermatids and mature sperm (By similarity). Using a GFP-fusion protein, detected in the nucleus.
Alternative names
SEPT10, SEPTIN10, Septin-10