Scamp5
Function
Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery (By similarity).
Sequence Similarities
Belongs to the SCAMP family. SCAMP5 subfamily.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
- Golgi apparatus membrane
- Multi-pass membrane protein
- Golgi apparatus
- trans-Golgi network membrane
- Multi-pass membrane protein
- Recycling endosome membrane
- Multi-pass membrane protein
- Cytoplasmic vesicle
- Secretory vesicle
- Synaptic vesicle membrane
- Multi-pass membrane protein
- Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it translocates to the cell membrane. Highly enriched in synaptic vesicles (By similarity).
Alternative names
Secretory carrier-associated membrane protein 5, Secretory carrier membrane protein 5