RBMS1

Developmental stage

Expressed at highest levels during the G1 to S transition of the cell cycle.

Function

Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.

Tissue Specificity

Highest amounts are found in placenta, lung and heart.

Cellular localization

• Nucleus

Alternative names

C2orf12, MSSP, MSSP1, SCR2, RBMS1, Single-stranded DNA-binding protein MSSP-1, Suppressor of CDC2 with RNA-binding motif 2

Database links

swissprot:P29558 entrezGene:5937 swissprot:Q6XE24 genbank:NP_058520.1 omim:602310