Nucleoside diphosphate-linked moiety X motif 19
Function
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity). Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity). Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
Sequence Similarities
Belongs to the Nudix hydrolase family.
Cellular localization
- Peroxisome
Alternative names
Acyl-coenzyme A diphosphatase NUDT19, Nucleoside diphosphate-linked moiety X motif 19, Nudix motif 19, NUDT19