Il2ra

Function

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

Cellular localization

• Membrane
• Single-pass type I membrane protein

Alternative names

CD25, Il2r, Il2ra, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, p55

Database links

swissprot:P01590 entrezGene:16184

Other research areas

• Immuno-oncology
• Neuroscience