HMMR
Function
Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity).
Tissue Specificity
Expressed in testis (PubMed:22965910). Expressed in the breast (PubMed:8890751).
Cellular localization
- Cell surface
- Cytoplasm
- Cytoplasm
- Cytoskeleton
- Spindle
Alternative names
CD168, IHABP, RHAMM, HMMR, Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility