HERC3
Function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Pathway
Protein modification; protein ubiquitination.
Post-translational modifications
Ubiquitinated; which promotes degradation by the proteasome.
Cellular localization
- Cytoplasm
- Cytoplasmic vesicle
- Also found in vesicular-like structures.
Alternative names
KIAA0032, HERC3, Probable E3 ubiquitin-protein ligase HERC3, HECT domain and RCC1-like domain-containing protein 3, HECT-type E3 ubiquitin transferase HERC3