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CSTF1

Domain

N-terminus mediates homodimerization.

Function

One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (PubMed:10669729). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (PubMed:10669729).

Post-translational modifications

The N-terminus is blocked.

Cellular localization

Alternative names

Cleavage stimulation factor subunit 1, CF-1 50 kDa subunit, Cleavage stimulation factor 50 kDa subunit, CSTF 50 kDa subunit, CstF-50, CSTF1

swissprot:Q05048 omim:600369 entrezGene:1477