ARL14
Function
GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.
Sequence Similarities
Belongs to the small GTPase superfamily. Arf family.
Tissue Specificity
Expressed in immature dendritic cells.
Cellular localization
- Cytoplasmic vesicle
- Colocalizes with MHC II-containing cytoplasmic vesicles.
Alternative names
ARF7, ARL14, ADP-ribosylation factor-like protein 14, ADP-ribosylation factor 7