AHSP
Function
Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.
Sequence Similarities
Belongs to the AHSP family.
Tissue Specificity
Expressed in blood and bone marrow.
Cellular localization
- Cytoplasm
Alternative names
EDRF, ERAF, AHSP, Alpha-hemoglobin-stabilizing protein, Erythroid differentiation-related factor, Erythroid-associated factor