ADSS2
Function
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Pathway
Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.
Sequence Similarities
Belongs to the adenylosuccinate synthetase family.
Cellular localization
- Cytoplasm
- Mitochondrion
- Partially associated with particulate fractions.
Alternative names
ADSS, ADSS2, Adenylosuccinate synthetase isozyme 2, AMPSase 2, AdSS 2, IMP--aspartate ligase 2, L-type adenylosuccinate synthetase