Anti-Somatostatin Receptor 2抗体- Extracellular domain (ab140933)
Key features and details
- Rabbit polyclonal to Somatostatin Receptor 2 - Extracellular domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
-
产品名称
Anti-Somatostatin Receptor 2抗体- Extracellular domain
参阅全部 Somatostatin Receptor 2 一抗 -
描述
兔多克隆抗体to Somatostatin Receptor 2 - Extracellular domain -
宿主
Rabbit -
特异性
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Horse, Cow, Dog, Pig, Monkey, Opossum, Common marmoset, Bat, Elephant -
免疫原
Synthetic peptide from 17 amino acid region within 2nd extracellular domain of Human Somatostatin Receptor 2 (P30874).
-
阳性对照
- Human pancreas, islet of Langerhans tissue
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. -
存储溶液
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab140933于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
Use a concentration of 24 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
说明 |
---|
IHC-P
Use a concentration of 24 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
-
功能
Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. -
组织特异性
Cerebrum and kidney. In lesser amounts in jejunum, colon and liver. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 282083 Cow
- Entrez Gene: 403472 Dog
- Entrez Gene: 100052744 Horse
- Entrez Gene: 6752 Human
- Entrez Gene: 20606 Mouse
- Entrez Gene: 497059 Pig
- Entrez Gene: 54305 Rat
- Omim: 182452 Human
see all -
别名
- Somatostatin receptor type 2 antibody
- SRIF-1 antibody
- SRIF1 antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab140933 被引用在 2 文献中.
- Sato A & Hara Y Protein expression of somatostatin receptor 2, somatostatin receptor 5 and dopamine D2 receptor in normal pituitary gland and ACTH-secreting pituitary adenoma in dogs. Res Vet Sci 119:61-66 (2018). IHC-P ; Dog . PubMed: 29864631
- Silva CB et al. Expression of somatostatin receptors (SSTR1-SSTR5) in meningiomas and its clinicopathological significance. Int J Clin Exp Pathol 8:13185-92 (2015). PubMed: 26722517