概述

  • 产品名称
    Anti-SLC25A20抗体
    参阅全部 SLC25A20 一抗
  • 描述
    兔多克隆抗体to SLC25A20
  • 宿主
    Rabbit
  • 经测试应用
    适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cynomolgus monkey
  • 免疫原

    Recombinant fragment corresponding to Human SLC25A20 aa 33-73.
    Sequence:

    TVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYR


    Database link: O43772

  • 阳性对照
    • IHC-P: Human small intestine tissue. WB: SLC25A20 overexpression HEK-293T lysate.

性能

应用

Our Abpromise guarantee covers the use of ab224388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/250. Predicted molecular weight: 33 kDa.

靶标

  • 相关性
    SLC25A20 is one of several closely related mitochondrial membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. It mediates the transport of acylcarnitines into the mitochondrial matrix for their oxidation by the mitochondrial fatty acid oxidation pathway. Mutations in this gene are associated with carnitine acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
  • 细胞定位
    Mitochondrion inner membrane; Multipass membrane protein.
  • 数据库链接
  • 别名
    • CAC antibody
    • CACT antibody
    • Carnitine/acylcarnitine translocase antibody
    • MCAT_HUMAN antibody
    • Mitochondrial carnitine/acylcarnitine carrier protein antibody
    • Solute carrier family 25 (carnitine/acylcarnitine translocase) member 20 antibody
    • Solute carrier family 25 member 20 antibody
    see all

图片

  • Paraffin-embedded human small intestine tissue stained for SLC25A20 using ab224388 at 1/50 dilution in immunohistochemical analysis.

  • All lanes : Anti-SLC25A20 antibody (ab224388) at 1/100 dilution

    Lane 1 : Vector only transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) lysate
    Lane 2 : SLC25A20 overexpression HEK-293T lysate (Co-expressed with a C-terminal myc-DDK tag, ~3.1 kDa)

    Predicted band size: 33 kDa

文献

ab224388 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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