SEN 12333,alpha7 nicotinic acetylcholine receptor (nAChR)激动剂(ab142237)
Key features and details
- Potent, selective α7 nicotinic acetylcholine receptor (nAChR) agonist
- CAS Number: 874450-44-9
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
SEN 12333,alpha7 nicotinic acetylcholine receptor (nAChR)激动剂 -
描述
Potent,selective α7 nicotinic acetylcholine receptor (nAChR)激动剂 -
生物学描述
Potent, selective α7 nicotinic acetylcholine receptor (nAChR) agonist. High affinity for rat α7 receptors (Ki = 260 nM). Full agonist in functional Ca2+ flux studies (EC50 = 1.6 μM). Active in vivo and in vitro. Excellent brain penetration. Orally bioavailable.
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纯度
> 98% -
CAS编号
874450-44-9 -
化学结构
性能
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化学名称
N-[4-(3-Pyridinyl)phenyl]-4-morpholinepentanamide -
分子量
339.44 -
分子式
C20H25N3O2 -
PubChem识别号
45484303 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(Nc1ccc(cc1)c2cccnc2)CCCCN3CCOCC3 -
来源
Synthetic
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研究领域
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
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