Anti-SEC61A抗体(ab1327)
Key features and details
- Goat polyclonal to SEC61A
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SEC61A抗体
参阅全部 SEC61A 一抗 -
描述
山羊多克隆抗体to SEC61A -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Cow, Dog, Pig
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免疫原
Synthetic peptide:
C-KEQSEVGSMGALLF
, corresponding to C terminal amino acids 463-476 of Human SEC61A(Peptide available as ab22804.) -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.05% Tris, 0.5% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).
1 hour primary incubation is recommended for this product. |
|
| IHC-P |
Use a concentration of 3.75 µg/ml.
|
| 说明 |
|---|
|
WB
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa). 1 hour primary incubation is recommended for this product. |
|
IHC-P
Use a concentration of 3.75 µg/ml. |
靶标
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功能
Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins. -
序列相似性
Belongs to the secY/SEC61-alpha family. -
细胞定位
Endoplasmic reticulum membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 505064 Cow
- Entrez Gene: 404006 Dog
- Entrez Gene: 29927 Human
- Omim: 609213 Human
- SwissProt: Q5EA68 Cow
- SwissProt: P38377 Dog
- SwissProt: P61619 Human
- Unigene: 518236 Human
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别名
- chunp6898 antibody
- fb62c11 antibody
- HSEC61 antibody
see all
图片
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Western blot - Anti-SEC61A antibody (ab1327)Anti-SEC61A antibody (ab1327) at 1 µg/ml + Human cerebellum lysate in RIPA buffer at 35 µg
Predicted band size: 52 kDa
实验方案
数据表及文件
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Datasheet download
文献 (1)
ab1327 被引用在 1 文献中.
- Lloyd DJ et al. A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice. Diabetes 59:460-70 (2010). ICC/IF ; Mouse . PubMed: 19934005
