Anti-SEC61A抗体(ab1327)

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Western blot - Anti-SEC61A antibody (ab1327)

    Key features and details

    • Goat polyclonal to SEC61A
    • Suitable for: WB, IHC-P
    • Reacts with: Human
    • Isotype: IgG

    概述

    • 产品名称

      Anti-SEC61A抗体
      参阅全部 SEC61A 一抗

    • 描述

      山羊多克隆抗体to SEC61A

    • 宿主

      Goat

    • 经测试应用

      适用于: WB, IHC-Pmore details

    • 种属反应性

      与反应: Human
      预测可用于: Cow, Dog, Pig

    • 免疫原

      Synthetic peptide:

      C-KEQSEVGSMGALLF

      , corresponding to C terminal amino acids 463-476 of Human SEC61A(Peptide available as ab22804.)
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • 常规说明

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    • 形式

      Liquid

    • 存放说明

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    • 存储溶液

      pH: 7.30
      Preservative: 0.02% Sodium azide
      Constituents: 0.05% Tris, 0.5% BSA
    • Concentration information loading...

    • 纯度

      Immunogen affinity purified

    • 纯化说明

      Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    • 克隆

      多克隆

    • 同种型

      IgG

    • 研究领域

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab1327于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).

    1 hour primary incubation is recommended for this product.
    IHC-P
    Use a concentration of 3.75 µg/ml.
    说明
    WB
    Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).

    1 hour primary incubation is recommended for this product.
    IHC-P
    Use a concentration of 3.75 µg/ml.

    靶标

    • 功能

      Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.

    • 序列相似性

      Belongs to the secY/SEC61-alpha family.

    • 细胞定位

      Endoplasmic reticulum membrane.
    • Information by UniProt

    • 数据库链接

      • 别名

        • chunp6898 antibody
        • fb62c11 antibody
        • HSEC61 antibody
        • protein transport protein SEC61 alpha subunit antibody
        • protein transport protein Sec61 subunit alpha antibody
        • Protein transport protein Sec61 subunit alpha isoform 1 antibody
        • S61A1_HUMAN antibody
        • SEC 61 antibody
        • SEC 61A antibody
        • Sec61 alpha 1 antibody
        • Sec61 alpha 1 subunit antibody
        • Sec61 alpha 1 subunit (S. cerevisiae) antibody
        • Sec61 alpha-1 antibody
        • SEC61 antibody
        • Sec61 homolog antibody
        • SEC61A1 antibody
        • sec61aa antibody
        see all

      图片

      • Western blot - Anti-SEC61A antibody (ab1327)
        Western blot - Anti-SEC61A antibody (ab1327)
        Anti-SEC61A antibody (ab1327) at 1 µg/ml + Human cerebellum lysate in RIPA buffer at 35 µg

        Predicted band size: 52 kDa

      文献 (1)

      发表研究结果有使用 ab1327？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab1327 被引用在 1 文献中.

      • Lloyd DJ  et al. A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice. Diabetes 59:460-70 (2010). ICC/IF ; Mouse . PubMed: 19934005

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