Anti-SEC61A抗体(ab1327)

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概述

  • 产品名称

    Anti-SEC61A抗体
    参阅全部 SEC61A 一抗

  • 描述

    山羊多克隆抗体to SEC61A

  • 宿主

    Goat

  • 经测试应用

    适用于: WB, IHC-P, ICC/IFmore details

  • 种属反应性

    与反应: Mouse, Human
    预测可用于: Cow, Dog, Pig

  • 免疫原

    Synthetic peptide:

    C-KEQSEVGSMGALLF

    , corresponding to C terminal amino acids 463-476 of Human SEC61A(Peptide available as ab22804.)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • 阳性对照

    • Human cerebellum and mouse brain lysate.

性能

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

  • 存储溶液

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.05% Tris, 0.5% BSA
  • Concentration information loading...

  • 纯度

    Immunogen affinity purified

  • 纯化说明

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

  • 克隆

    多克隆

  • 同种型

    IgG

  • 研究领域

应用

Our Abpromise guarantee covers the use of ab1327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).
IHC-P Use a concentration of 3.75 µg/ml.
ICC/IF Use at an assay dependent concentration. PubMed: 19934005

靶标

  • 功能

    Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.

  • 序列相似性

    Belongs to the secY/SEC61-alpha family.

  • 细胞定位

    Endoplasmic reticulum membrane.
  • Information by UniProt

  • 数据库链接

    see all

  • 别名

    • chunp6898 antibody
    • fb62c11 antibody
    • HSEC61 antibody
    • protein transport protein SEC61 alpha subunit antibody
    • protein transport protein Sec61 subunit alpha antibody
    • Protein transport protein Sec61 subunit alpha isoform 1 antibody
    • S61A1_HUMAN antibody
    • SEC 61 antibody
    • SEC 61A antibody
    • Sec61 alpha 1 antibody
    • Sec61 alpha 1 subunit antibody
    • Sec61 alpha 1 subunit (S. cerevisiae) antibody
    • Sec61 alpha-1 antibody
    • SEC61 antibody
    • Sec61 homolog antibody
    • SEC61A1 antibody
    • sec61aa antibody
    see all

图片

  • Western blot - Anti-SEC61A antibody (ab1327)
    Western blot - Anti-SEC61A antibody (ab1327)
    Anti-SEC61A antibody (ab1327) at 1 µg/ml + Human cerebellum lysate in RIPA buffer at 35 µg

    Predicted band size: 52 kDa

文献

This product has been referenced in:

  • Lloyd DJ  et al. A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice. Diabetes 59:460-70 (2010). ICC/IF ; Mouse . Read more (PubMed: 19934005) »
See 1 Publication for this product

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