Anti-SDS3抗体(ab3740)
Key features and details
- Goat polyclonal to SDS3
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
-
产品名称
Anti-SDS3抗体
参阅全部 SDS3 一抗 -
描述
山羊多克隆抗体to SDS3 -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rabbit, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
-
免疫原
Synthetic peptide (Human) - which represented a portion of human Suppressor of Defective Silencing 3 encoded in part by exons 7 and 8.
-
常规说明
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
Our Abpromise guarantee covers the use of ab3740 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | 1/1000 - 1/5000. Predicted molecular weight: 45 kDa. |
靶标
-
功能
Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. -
组织特异性
Expressed in various cancer cell ines. -
序列相似性
Belongs to the SDS3 family. -
结构域
The C-terminus is involved in transcriptional repression by HDAC-independent mechanisms. - Information by UniProt
-
数据库链接
- Entrez Gene: 64426 Human
- Entrez Gene: 71954 Mouse
- Entrez Gene: 445099 Zebrafish
- Omim: 608250 Human
- SwissProt: Q9H7L9 Human
- SwissProt: Q8BR65 Mouse
- SwissProt: Q803C3 Zebrafish
- Unigene: 416630 Human
see all -
别名
- 2400003N08Rik antibody
- 2410008L21Rik antibody
- 45 kDa Sin3 associated polypeptide antibody
see all
图片
-
Western blot - Anti-SDS3 antibody (ab3740)
Sample: HeLa whole cell lysate (50
µ g/lane)Antibody: Affinity purified Goat anti-SDS 3 (ab3740) used at the concentrations indicated.
Detection: ECL exposed for 2 minutes.
Sample: HeLa whole cell lysate (50
µg/lane) Antibody: Affinity purified Goat anti-SDS 3 (ab3740) used at the concentrations indicated.
Detection: ECL exposed for 2 minutes.
文献 (2)
ab3740 被引用在 2 文献中.
- Ramakrishna S et al. Hyaluronan Binding Motifs of USP17 and SDS3 Exhibit Anti-Tumor Activity. PLoS One 7:e37772 (2012). WB ; Human . PubMed: 22662218
- Ramakrishna S et al. K63 specific deubiquitination of SDS3 by USP17 regulates HDAC activity. J Biol Chem : (2011). IP ; Human . PubMed: 21239494
