概述

  • 产品名称
  • 描述
    兔多克隆抗体to SCP1
  • 宿主
    Rabbit
  • 经测试应用
    适用于: IHC-Fr, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Synthetic peptide (Mouse) (C terminal).

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.1% Sodium azide
    Constituent: Tris citrate/phosphate
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab15090 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/750.
IHC-P 1/750.
ICC/IF 1/100 - 1/750.

靶标

  • 功能
    Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.
  • 组织特异性
    Testis.
  • 结构域
    Consists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity.
  • 细胞定位
    Nucleus. Chromosome. In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cancer/testis antigen 8 antibody
    • CT8 antibody
    • HOM TES 14 antibody
    • MGC104417 antibody
    • SCP 1 antibody
    • SCP-1 antibody
    • SCP1 antibody
    • SYCP 1 antibody
    • Sycp1 antibody
    • SYCP1_HUMAN antibody
    • Synaptonemal complex protein 1 antibody
    • Testicular tissue protein Li 191 antibody
    see all

图片

  • SCP1 labeled in mouse pachytene preparation (red), using ab15090. CDK2 staining, near teleomeres, is also present (green).
  • Paraffin embeded IHC image of Murine SCP1 in mouse ovary using ab15090 at 1:750 dilution and secondary at 1:400.

文献

This product has been referenced in:
See all 45 Publications for this product

客户评价及客户问答

1-2 of 2 Q&A

Answer

Thank you for contacting Abcam.

Under our Abpromise we guarantee our products for 6 months from the date of delivery and so it is no longer covered under this guarantee. I will be more than happy to help you troubleshoot your protocol to see if there are any changes that I can suggest that will help.

Also, if you are concerned that the staining pattern is incorrect, I would recommend speaking to your lab colleague as to why they felt the staining was specific enough to publish with and also why they did not question the specificity of the antibody. Also were you using the exact same protocol as your lab colleague?

Please let me know if there is anything else I can help you with.

Read More

Answer

I can confirm that ab15090 is not likely to cross react with human as the immunogen shares only 83% homology with the human protein. Unfortunately ab15087 will work in human but does not appear to work in immunohistochemistry on paraffin-embedded sections. I'm sorry we don't appear to have a product suitable for your needs at the moment,

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册