Anti-RRBP1抗体(ab95983)
Key features and details
- Rabbit polyclonal to RRBP1
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
概述
-
产品名称
Anti-RRBP1抗体
参阅全部 RRBP1 一抗 -
描述
兔多克隆抗体to RRBP1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-P, ICC/IFmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
-
阳性对照
- WB: NIH-3T3 whole cell lysate. IHC-P: OVCAR3 cell ICC/IF: HeLa cell
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 59.99% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95983于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 109 kDa.
|
|
| IHC-P |
1/100 - 1/1000.
|
|
| ICC/IF |
1/100 - 1/1000.
|
| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 109 kDa. |
|
IHC-P
1/100 - 1/1000. |
|
ICC/IF
1/100 - 1/1000. |
靶标
-
功能
Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane. -
细胞定位
Endoplasmic reticulum membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 6238 Human
- Entrez Gene: 81910 Mouse
- Omim: 601418 Human
- SwissProt: Q9P2E9 Human
- SwissProt: Q99PL5 Mouse
- Unigene: 472213 Human
- Unigene: 13705 Mouse
-
别名
- 180 kDa ribosome receptor homolog antibody
- DKFZp586A1420 antibody
- ES/130 antibody
see all
图片
-
Immunocytochemistry/ Immunofluorescence - Anti-RRBP1 antibody (ab95983)Immunofluorescence analysis of paraformaldehyde fixed HeLa, using ab95983 at 1/200 dilution. Lower image merged with DNA probe.
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RRBP1 antibody (ab95983)Immunohistochemical analysis of paraffin embedded OVCAR3, using ab95983 at 1/500 dilution. -
Western blot - Anti-RRBP1 antibody (ab95983)Anti-RRBP1 antibody (ab95983) at 1/1000 dilution + NIH 3T3 whole cell lysate at 30 µg
Predicted band size: 109 kDa
5% SDS PAGE
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (11)
ab95983 被引用在 11 文献中.
- Shriwas O et al. RRBP1 rewires cisplatin resistance in oral squamous cell carcinoma by regulating Hippo pathway. Br J Cancer 124:2004-2016 (2021). PubMed: 33762722
- Özkan N et al. ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability. Nat Commun 12:4493 (2021). PubMed: 34301956
- Luo HL et al. Hypomethylated RRBP1 Potentiates Tumor Malignancy and Chemoresistance in Upper Tract Urothelial Carcinoma. Int J Mol Sci 22:N/A (2021). PubMed: 34445467
- Wang M et al. RRBP1 is highly expressed in bladder cancer and is associated with migration and invasion. Oncol Lett 20:203 (2020). PubMed: 32963609
- Zhu J et al. Correlation between reticulum ribosome-binding protein 1 (RRBP1) overexpression and prognosis in cervical squamous cell carcinoma. Biosci Trends 14:279-284 (2020). PubMed: 32536673