Anti-RPIA/PRI抗体(ab229967)
Key features and details
- Rabbit polyclonal to RPIA/PRI
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-RPIA/PRI抗体
参阅全部 RPIA/PRI 一抗 -
描述
兔多克隆抗体to RPIA/PRI -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Cow, Pig -
免疫原
Recombinant fragment corresponding to Human RPIA/PRI aa 50 to the C-terminus.
Database link: P49247 -
阳性对照
- WB: Mouse kidney lysate. IHC-P: Human placenta and gastric cancer tissues.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab229967于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/5000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).
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IHC-P |
1/20 - 1/200.
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说明 |
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WB
1/1000 - 1/5000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa). |
IHC-P
1/20 - 1/200. |
靶标
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通路
Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. -
疾病相关
Defects in RPIA are the cause of ribose 5-phosphate isomerase deficiency (RPID) [MIM:608611]. A patient has been described with a deficiency of ribose 5-phosphate isomerase who presented with leukoencephalopathy and peripheral neuropathy. Proton magnetic resonance spectroscopy of the brain revealed a highly elevated level of the polyols ribitol and D-arabitol, which were subsequently also found in high concentrations in body fluids. Deficient activity of RPIA, one of the pentose phosphate pathway enzymes, has been demonstrated in fibroblasts. -
序列相似性
Belongs to the ribose 5-phosphate isomerase family. - Information by UniProt
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数据库链接
- Entrez Gene: 613376 Cow
- Entrez Gene: 22934 Human
- Entrez Gene: 19895 Mouse
- Entrez Gene: 100038014 Pig
- Omim: 180430 Human
- SwissProt: Q3T186 Cow
- SwissProt: P49247 Human
- SwissProt: P47968 Mouse
see all -
别名
- EC 5.3.1.6 antibody
- MGC103524 antibody
- Phosphoriboisomerase A antibody
see all
图片
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Paraffin-embedded human gastric cancer tissue stained for RPIA/PRI using ab229967 at 1/100 dilution in immunohistochemical analysis.
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Paraffin-embedded human placenta tissue stained for RPIA/PRI using ab229967 at 1/100 dilution in immunohistochemical analysis.
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Anti-RPIA/PRI antibody (ab229967) at 1/1000 dilution + Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab229967 尚未被引用在任何文献中。