Key features and details
- Rabbit polyclonal to Retinoic Acid Receptor gamma 1
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
产品名称Anti-Retinoic Acid Receptor gamma 1抗体
描述兔多克隆抗体to Retinoic Acid Receptor gamma 1
经测试应用适用于: WBmore details
种属反应性与反应: Mouse, Human
存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液Preservative: 0.05% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab5904 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000. Detects a band of approximately 50 kDa (predicted molecular weight: 54 kDa).Can be blocked with Human Retinoic Acid Receptor gamma 1 peptide (ab39773).|
|EMSA||Use 1µl for 102 cells.
Use 1-2µl. ab5904 has been shown to efficiently super shift the human RAR gamma-1/retinoid X receptor (RXR)/RAR response element complex in gel super shift experiments using a number of different response elements.
功能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
- Information by UniProt
- NR1B3 antibody
- Nuclear receptor subfamily 1 group B member 3 antibody
- RAR gamma antibody
ab5904 被引用在 2 文献中.
- Kadigamuwa C et al. Role of Retinoic Acid Receptor-? in DNA Damage-Induced Necroptosis. iScience 17:74-86 (2019). PubMed: 31255985
- Joss-Moore L et al. Intrauterine growth restriction transiently delays alveolar formation and disrupts retinoic acid receptor expression in the lung of female rat pups. Pediatr Res 73:612-20 (2013). PubMed: 23419538