Anti-Retinoic Acid Receptor beta抗体(ab5792)
Key features and details
- Rabbit polyclonal to Retinoic Acid Receptor beta
- Suitable for: WB
- Reacts with: Mouse, Human, Saccharomyces cerevisiae
- Isotype: IgG
概述
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产品名称
Anti-Retinoic Acid Receptor beta抗体
参阅全部 Retinoic Acid Receptor beta 一抗 -
描述
兔多克隆抗体to Retinoic Acid Receptor beta -
宿主
Rabbit -
特异性
This antibody shows slight cross-reactivity to RAR alpha but does not detect RAR gamma. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human, Saccharomyces cerevisiae -
免疫原
Synthetic peptide corresponding to Mouse Retinoic Acid Receptor beta aa 429-448.
Sequence:PSUSPSSVENSGVSQSPLLQ
(Peptide available asab5897) -
阳性对照
- SH-SY5Y cell extract.
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常规说明
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
Our Abpromise guarantee covers the use of ab5792 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | 1/1000. Detects a band of approximately 52 kDa (predicted molecular weight: 53 kDa). |
靶标
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功能
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function. -
疾病相关
Microphthalmia, syndromic, 12 -
序列相似性
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
结构域
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. -
细胞定位
Cytoplasm and Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 5915 Human
- Entrez Gene: 218772 Mouse
- Omim: 180220 Human
- SwissProt: P10826 Human
- SwissProt: P22605 Mouse
- Unigene: 543218 Human
- Unigene: 581530 Human
- Unigene: 654490 Human
see all -
别名
- HAP antibody
- HBV-activated protein antibody
- NR1B2 antibody
see all
图片
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Western blot - Anti-Retinoic Acid Receptor beta antibody (ab5792)All lanes : Anti-Retinoic Acid Receptor beta antibody (ab5792) at 1/1000 dilution
Lane 1 : SH-SY5Y cell lysate
Lane 2 : HepG2 cell lysate
Lane 3 : Mouse heart cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 53 kDa
Observed band size: 58 kDa why is the actual band size different from the predicted?
数据表及文件
文献 (0)
ab5792 尚未被引用在任何文献中。
