重组恒河猴CD40蛋白(Fc Chimera) (ab208480)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
描述
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产品名称
重组恒河猴CD40蛋白(Fc Chimera)
参阅全部 CD40 蛋白酶 -
生物活性
Measured by its binding ability in a functional ELISA. Immobilized ab208480 at 2μg/mL (100 µl/well), can bind Recombinant Human CD40LG /CD40 Ligand Protein with a linear of 5-50 ng/mL.
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纯度
> 95 % SDS-PAGE. -
内毒素水平
< 1.000 Eu/µg -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Rhesus monkey -
序列
EPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCSESEFLDT WNRETRCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGLHCMSESCESCV PHRSCLPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCRPWTSCETK DLVVQQAGTNKTDVVCGPQDRQR -
预测分子量
46 kDa including tags -
氨基酸
21 to 193 -
额外的序列信息
Chimera fused with a Human IgG1 Fc tag at the C-terminus (NP_001252791.1).
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技术指标
Our Abpromise guarantee covers the use of ab208480 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -80°C.
pH: 7.40
Constituents: 0.61% Tris, 0.75% Glycine, 5% Trehalose, 0.44% L-Arginine, 0.87% Sodium chloride
Note: 5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%.This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Reconstitute with sterile deionized water to a concentration of 250 µg/ml.
常规信息
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别名
- AI326936
- B cell associated molecule CD40
- B cell surface antigen CD40
see all -
功能
Receptor for TNFSF5/CD40LG. -
组织特异性
B-cells and in primary carcinomas. -
疾病相关
Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. -
序列相似性
Contains 4 TNFR-Cys repeats. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab208480 尚未被引用在任何文献中。