重组大鼠IL-2蛋白(ab644)
描述
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产品名称
重组大鼠IL-2蛋白
参阅全部 IL-2 蛋白酶 -
内毒素水平
< 0.100 Eu/µg -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Rat -
序列
Recombinant rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues. MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM
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技术指标
Our Abpromise guarantee covers the use of ab644 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Lyophilised -
补充说明
The ED50, determined by the dose-dependent stimulation of murine CTLL-2 cells, is < 0.4 ng/ml, corresponding to a specific activity of > 2.5 x 106 units/mg. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.
n/a
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Reconstitute with 20µl pure water.
常规信息
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别名
- Aldesleukin
- IL 2
- IL-2
see all -
功能
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. -
疾病相关
Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. -
序列相似性
Belongs to the IL-2 family. -
细胞定位
Secreted. - Information by UniProt
数据表及文件
文献
ab644 has not yet been referenced specifically in any publications.
