重组大鼠IL-2蛋白(ab644)

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Key features and details

  • Expression system: Escherichia coli
  • Purity: > 98% SDS-PAGE
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

描述

  • 产品名称

    重组大鼠IL-2蛋白
    参阅全部 IL-2 蛋白酶

  • 纯度

    > 98 % SDS-PAGE.
    Endotoxin level is less than 0.1 ng per g (1EU/g).

  • 表达系统

    Escherichia coli

  • 蛋白长度

    Full length protein

  • 无动物成分

    No

  • 性质

    Recombinant

    • 种属

      Rat

    • 序列

      Recombinant rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues. MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM

技术指标

Our Abpromise guarantee covers the use of ab644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 形式

    Lyophilized

  • 补充说明

    The ED50, determined by the dose-dependent stimulation of murine CTLL-2 cells, is < 0.4 ng/ml, corresponding to a specific activity of > 2.5 x 106 units/mg.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶
    Reconstitute with 20µl pure water.

常规信息

  • 别名

    • Aldesleukin
    • IL 2
    • IL-2
    • IL2
    • IL2_HUMAN
    • Interleukin 2
    • Interleukin-2
    • interleukin2
    • Involved in regulation of T cell clonal expansion
    • Lymphokine
    • OTTHUMP00000164090
    • POIL2
    • T Cell Growth Factor
    • T-cell growth factor
    • TCGF
    see all

  • 功能

    Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

  • 疾病相关

    Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.

  • 序列相似性

    Belongs to the IL-2 family.

  • 细胞定位

    Secreted.
  • Information by UniProt

实验方案

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

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