重组人SNRPD3/Sm-D3蛋白(ab113120)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: MS, SDS-PAGE
描述
-
产品名称
重组人SNRPD3/Sm-D3蛋白 -
纯度
> 85 % SDS-PAGE.
ab113120 was purified using conventional chromatography. -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
MGSSHHHHHHSSGLVPRGSHMSIGVPIKVLHEAEGHIVTCETNTGEVYRG KLIEAEDNMNCQMSNITV TYRDGRVAQLEQVYIRGSKIRFLILPDMLK NAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQ KRR -
预测分子量
16 kDa including tags -
氨基酸
1 to 126 -
标签
His tag N-Terminus
-
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab113120 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Mass Spectrometry
SDS-PAGE
-
质谱法
MALDI-TOF -
形式
Liquid -
补充说明
Previously labelled as SNRPD3.
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.002% PMSF, 0.03% DTT, 0.32% Tris HCl, 40% Glycerol (glycerin, glycerine), 2.92% Sodium chloride
常规信息
-
别名
- Sm D3
- Sm-D3
- small nuclear ribonucleoprotein D3 polypeptide 18kDa
see all -
功能
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. -
序列相似性
Belongs to the snRNP core protein family. -
翻译后修饰
Methylated on arginine residues by PRMT5 and PRMT7; methylation is required for assembly and biogenesis of snRNPs.
Arg-97 is dimethylated, probably to asymmetric dimethylarginine. -
细胞定位
Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab113120 被引用在 1 文献中.
- Metz PJ et al. Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling. Cell Rep 30:1935-1950.e8 (2020). PubMed: 32049022