重组人PCBP2/hnRNP E2蛋白(ab152593)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
描述
-
产品名称
重组人PCBP2/hnRNP E2蛋白 -
表达系统
Wheat germ -
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
VTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPL EAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG YWAGLDASAQ -
氨基酸
174 to 283 -
标签
GST tag N-Terminus
-
技术指标
Our Abpromise guarantee covers the use of ab152593 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
ELISA
Western blot
-
形式
Liquid -
补充说明
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
-
别名
- Alpha CP2
- Alpha-CP2
- alphaCP-2
see all -
功能
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation. -
组织特异性
Detected in all tissues examined. -
序列相似性
Contains 3 KH domains. -
翻译后修饰
Phosphorylated. The non-phosphorylated form(s) exhibited the strongest poly(rC)-binding activity. -
细胞定位
Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab152593 尚未被引用在任何文献中。