重组人IL2 Receptor beta/p75蛋白(Fc Chimera) (ab84068)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE
描述
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产品名称
重组人IL2 Receptor beta/p75蛋白(Fc Chimera)
参阅全部 IL2 Receptor beta/p75 蛋白酶 -
生物活性
ab84068 bound to protein A sepharose beads is able to pull down its ligand, IL2. -
纯度
> 95 % SDS-PAGE. -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
Theoretical Sequence: AVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWP DRRRWNQ TCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREG VRWRVMAI QDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYF ERHLEFEART LSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVR VKPLQGEFTTW SPWSQPLAFRTKPAALGIPKVDKKVEPKSCDKTHTCP PCPAPELLGGPS VFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKF NWYVDGVEVHNAK TKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKV SNKALPAPIEKTIS KAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKG FYPSDIAVEWESNG QPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQ GNVFSCSVMHEALH NHYTQKSLSLSPGK -
氨基酸
27 to 237 -
额外的序列信息
DNA sequence encoding the signal peptide and extracellular domain of human IL 2R beta (aa 1-237) was fused to the Fc region of human IgG1 (aa93-330). Protein expressed in modified human 293 cells.
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技术指标
Our Abpromise guarantee covers the use of ab84068 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Lyophilized -
补充说明
ab84068 bound to protein A sepharose beads is able to pull down its ligand, IL2.This product was previously labelled as IL2 Receptor beta
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Constituents: 1% Human serum albumin, 10% Trehalose
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial. Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.
常规信息
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别名
- CD122
- CD122 antigen
- High affinity IL 2 receptor beta subunit
see all -
功能
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. -
序列相似性
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 1 fibronectin type-III domain. -
结构域
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
细胞定位
Membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab84068 尚未被引用在任何文献中。