概述

描述

  • 性质
    Recombinant
  • 来源
    BTI-TN-5B1-4 cells
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 分子量
      80 kDa
    • 氨基酸
      32 to 728
    • 额外的序列信息
      Mature protein without signal peptide consisting of HGF alpha and beta chain.

技术指标

Our Abpromise guarantee covers the use of ab632 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 形式
    Lyophilised
  • 补充说明
    The ED50, determined by the dose-dependent stimulation of the proliferation of monkey 4MBr-5 cells, was found to be in the range of 20.0 - 40.0 ng/ml. Expression System = Baculovirus infected High-5 cells.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 1.16% Sodium chloride, 0.12% Tris, 1.74% DL-Arginine

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶
    Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

常规信息

  • 别名
    • DFNB39
    • F TCF
    • Fibroblast derived tumor cytotoxic factor
    • Hepatocyte growth factor
    • Hepatocyte growth factor (hepapoietin A; scatter factor)
    • Hepatocyte growth factor beta chain
    • Hepatocyte growth factor precursor
    • Hepatopoietin A
    • Hepatopoietin-A
    • Hgf
    • HGF_HUMAN
    • HGFB
    • HPTA
    • Lung fibroblast derived mitogen
    • OTTHUMP00000161349
    • OTTHUMP00000206710
    • OTTHUMP00000206711
    • OTTHUMP00000206712
    • OTTHUMP00000206713
    • OTTHUMP00000206730
    • Scatter factor
    • SF
    see all
  • 功能
    Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
  • 疾病相关
    Deafness, autosomal recessive, 39
  • 序列相似性
    Belongs to the peptidase S1 family. Plasminogen subfamily.
    Contains 4 kringle domains.
    Contains 1 PAN domain.
    Contains 1 peptidase S1 domain.
  • Information by UniProt

图片

  • Standard curve for HGF (Analyte: ab632); dilution range 1pg/ml to 1µg/ml using Capture Antibody ab10829 at 5µg/ml and Detector Antibody ab24865 at 0.5µg/ml.

文献

ab632 has not yet been referenced specifically in any publications.

客户评价及客户问答

Question
Answer

I can confirm the product ab632 human HGF is supplied as the active (mature form). Please contact us again if you need further information,

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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