重组人Cytochrome P450 1A2蛋白(ab158245)
Key features and details
- Expression system: Wheat germ
- Purity: > 99% Proprietary Purification
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
描述
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产品名称
重组人Cytochrome P450 1A2蛋白 -
纯度
> 99 % Proprietary Purification. -
表达系统
Wheat germ -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPL LGHVLTLGKNPHLALSRMSQRYGDVLQIRIDSTPVLVLSRLDTIRQALVR QGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVI GAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPAL QRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGN LIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTV IGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFY IPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMML FGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMK HARCEHVQARLRFSIN -
氨基酸
1 to 516 -
标签
GST tag N-Terminus
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技术指标
Our Abpromise guarantee covers the use of ab158245 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
ELISA
Western blot
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形式
Liquid -
补充说明
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- Aryl hydrocarbon hydroxylase
- CP 12
- CP12
see all -
功能
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. -
组织特异性
Liver. -
序列相似性
Belongs to the cytochrome P450 family. -
细胞定位
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab158245 尚未被引用在任何文献中。