重组人CLLD8/SETDB2蛋白(ab169554)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 80% Densitometry
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人CLLD8/SETDB2蛋白 -
纯度
> 80 % Densitometry.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYI QAMILVNEATIINSSTSIKDPMPVTQKEQENKSNAFPSTSCENSFPEDCT FLTTGNKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGE NPLQLPIKCHFQRRHAKTNSHSSALHVSYKTPCGRSLRNVEEVFRYLLET ECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEID SRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTA RNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQ HGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGI DENGRDENTMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPP KFSNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSE SVTPEDNDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDIT KYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCD EELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQN VFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVN KCRKKIL -
预测分子量
120 kDa including tags -
氨基酸
1 to 719 -
标签
GST tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab169554 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
常规信息
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别名
- C13orf4
- Chromosome 13 open reading frame 4
- Chronic lymphocytic leukemia deletion region 8
see all -
功能
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis. -
组织特异性
Ubiquitous. Highest expression in heart, testis and ovary. -
序列相似性
Belongs to the histone-lysine methyltransferase family.
Contains 1 MBD (methyl-CpG-binding) domain.
Contains 1 pre-SET domain.
Contains 1 SET domain. -
细胞定位
Nucleus. Chromosome. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab169554 被引用在 1 文献中.
- Li H et al. MiR-122 Promotes the Development of Colon Cancer by Targeting ALDOA In Vitro. Technol Cancer Res Treat 18:1533033819871300 (2019). PubMed: 31564215