重组人CD20蛋白(ab158047)
Key features and details
- Expression system: Wheat germ
- Purity: > 80% n/a
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, ELISA, WB
描述
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产品名称
重组人CD20蛋白
参阅全部 CD20 蛋白酶 -
纯度
> 80 % n/a.
Glutathione Sepharose 4 Fast Flow -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESK TLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSL LAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKME SLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIF AFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLT ETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP -
预测分子量
58 kDa including tags -
氨基酸
1 to 297 -
标签
GST tag N-Terminus
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技术指标
Our Abpromise guarantee covers the use of ab158047 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
ELISA
Western blot
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形式
Liquid -
补充说明
Concentration of ab158047 is lot specific, the displayed concentration is for the available lots.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- APY
- ATOPY
- B lymphocyte antigen CD20
see all -
功能
This protein may be involved in the regulation of B-cell activation and proliferation. -
组织特异性
Expressed on B-cells. -
疾病相关
Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
序列相似性
Belongs to the MS4A family. -
翻译后修饰
Phosphorylated. Might be functionally regulated by protein kinase(s). -
细胞定位
Membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab158047 尚未被引用在任何文献中。