重组人BMP3蛋白(ab97412)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 0.100 Eu/µg
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE, HPLC
描述
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产品名称
重组人BMP3蛋白 -
生物活性
Determined by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC-5 cells. -
纯度
> 95 % SDS-PAGE.
Purity is greater than 95% by SDS-PAGE gel and HPLC analyses. -
内毒素水平
< 0.100 Eu/µg -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MQWIEPRNCA RRYLKVDFAD IGWSEWIISP KSFDAYYCSG ACQFPMPKSL KPSNHATIQS IVRAVGVVPG IPEPCCVPEK MSSLSILFFD ENKNVVLKVY PNMTVESCAC R -
预测分子量
13 kDa -
氨基酸
363 to 472
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab97412 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
HPLC
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形式
Lyophilized -
补充说明
Determined by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC-5 cells. Determined by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC-5 cells. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶The lyophilized protein is stable at room temperature for up to 1 month. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C.
常规信息
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别名
- BMP-3
- BMP-3A
- bmp3
see all -
功能
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. -
组织特异性
Expressed in adult and fetal cartilage. -
序列相似性
Belongs to the TGF-beta family. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (1)
ab97412 被引用在 1 文献中.
- Spurlin JW et al. BMP3 inhibits TGFβ2-mediated myofibroblast differentiation during wound healing of the embryonic cornea. NPJ Regen Med 7:36 (2022). PubMed: 35879352