重组人BMP1 / PCP蛋白(ab114558)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIES QPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDN
    • 分子量
      37 kDa including tags
    • 氨基酸
      747 to 845

相关产品

技术指标

Our Abpromise guarantee covers the use of ab114558 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明

    Protein previously labeled as BMP1.

    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • BMP 1
    • BMP-1
    • BMP1
    • BMP1_HUMAN
    • Bone morphogenetic protein 1
    • Mammalian tolloid protein
    • mTld
    • OI13
    • PCOLC
    • PCP
    • PCP2
    • Procollagen C endopeptidase
    • Procollagen C proteinase
    • Procollagen C-proteinase
    • TLD
    • Tolloid, Drosophila, homolog of
    see all
  • 功能
    Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX.
  • 组织特异性
    Ubiquitous.
  • 疾病相关
    Osteogenesis imperfecta 13
  • 序列相似性
    Belongs to the peptidase M12A family.
    Contains 5 CUB domains.
    Contains 2 EGF-like domains.
  • 翻译后修饰
    Proteolytically activated in the trans-Golgi network by furin-like/paired basic proprotein convertases, cleavage is not required for secretion.
  • 细胞定位
    Golgi apparatus, trans-Golgi network. Secreted, extracellular space, extracellular matrix. Co-localizes with POSTN in the Golgi.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE Stained with Coomassie Blue

文献

ab114558 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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