概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MEATGTDEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHF KYEDEDKTLPAESGCTIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEG SALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTWPDALNIENSDSESWT SHTVKKFTASFEASLSGEREFKTPTISLKETIGKYSDDHEMRNEVYHRKI ISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHILRKAVEEARH PDLQGITIYVAQDCTVYNSDVIDKQSASMTSDNADDKAVIILVPVRLGGE RTNTDYLEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQ SFVDVSIKDFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEE ITKMLKFSSKEKYPLFTFVNGHSRDYDFTSTTTNEEDLFSEDEKKQLKRF STEEFVLL
    • 氨基酸
      1 to 458
    • 标签
      proprietary tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab153559 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • APG4 autophagy 4 homolog C
    • APG4 autophagy 4 homolog C (S. cerevisiae)
    • APG4 C
    • APG4-C
    • APG4C
    • ATG 4C
    • ATG4 autophagy related 4 homolog C
    • ATG4 autophagy related 4 homolog C (S. cerevisiae)
    • Atg4c
    • ATG4C_HUMAN
    • AUT (S. cerevisiae) like 1, cysteine endopeptidase
    • AUT like 1, cysteine endopeptidase
    • AUT like 1, cysteine endopeptidase (S. cerevisiae)
    • AUT like 3 cysteine endopeptidase
    • AUT-like 3 cysteine endopeptidase
    • AUTL1
    • AUTL3
    • Autophagin 3
    • Autophagin-3
    • Autophagy related 4C cysteine peptidase
    • Autophagy related cysteine endopeptidase 3
    • Autophagy related protein 4 homolog C
    • Autophagy-related cysteine endopeptidase 3
    • Autophagy-related protein 4 homolog C
    • Cysteine protease ATG4C
    • EC 3.4.22
    • FLJ14867
    • OTTHUMP00000010715
    see all
  • 功能
    Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
  • 组织特异性
    Highly expressed in skeletal muscle, heart, liver and testis.
  • 序列相似性
    Belongs to the peptidase C54 family.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • ab153559 on a 12.5% SDS-PAGE stained with Coomassie Blue.

文献

ab153559 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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