The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Apoptosis signal regulating kinase 1
Apoptosis signal-regulating kinase 1
MAP/ERK kinase kinase 5
MAPK/ERK kinase kinase 5
MEK kinase 5
Mitogen activated protein kinase kinase kinase 5
Mitogen-activated protein kinase kinase kinase 5
Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
Abundantly expressed in heart and pancreas.
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 protein kinase domain.