Anti-RB-1抗体(ab224426)
Key features and details
- Rabbit polyclonal to RB-1
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-RB-1抗体 -
描述
兔多克隆抗体to RB-1 -
宿主
Rabbit -
经测试应用
适用于: ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment corresponding to Human RB-1 aa 1-150.
Database link: Q8IUH3 -
阳性对照
- ICC/IF: U-2 OS cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol, PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab224426于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100. |
说明 |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. Fixation/Permeabilization: PFA/Triton X-100. |
靶标
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功能
RNA-binding protein with binding specificity for poly(C). May play an important role in neural development. -
序列相似性
Contains 3 RRM (RNA recognition motif) domains. -
细胞定位
Cytoplasm. Nucleus. Predominantly cytoplasmic. May shuttle between cytoplasm and nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 129831 Human
- Entrez Gene: 241490 Mouse
- Entrez Gene: 266631 Rat
- Omim: 608888 Human
- SwissProt: Q8IUH3 Human
- SwissProt: Q8BHN5 Mouse
- SwissProt: Q8CFD1 Rat
- Unigene: 377257 Human
see all -
别名
- Developmentally-regulated RNA-binding protein 1 antibody
- DRB1 antibody
- FLJ44612 antibody
see all
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab224426 被引用在 2 文献中.
- Liu Y et al. miR-222-5p promotes dysfunction of human vascular smooth muscle cells by targeting RB1. Environ Toxicol 37:683-694 (2022). PubMed: 34862716
- Yuan XW et al. Effect of miR-515-5p on Proliferation and Drug Sensitivity of Retinoblastoma Cells. Cancer Manag Res 12:12087-12098 (2020). PubMed: 33262657