Anti-RanBP1抗体(ab2937)
Key features and details
- Rabbit polyclonal to RanBP1
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
-
产品名称
Anti-RanBP1抗体
参阅全部 RanBP1 一抗 -
描述
兔多克隆抗体to RanBP1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Cow
-
免疫原
Synthetic peptide corresponding to Human RanBP1 aa 1-18.
Sequence:MAAAKDTHEDHDTSTENT
(Peptide available asab4938) -
阳性对照
- HeLa cell lysate
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 99% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 24 kDa).
|
| 说明 |
|---|
|
WB
Use a concentration of 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 24 kDa). |
靶标
-
功能
Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane. -
序列相似性
Belongs to the RANBP1 family.
Contains 1 RanBD1 domain. - Information by UniProt
-
数据库链接
- Entrez Gene: 533251 Cow
- Entrez Gene: 5902 Human
- Entrez Gene: 19385 Mouse
- Omim: 601180 Human
- SwissProt: Q3T0M7 Cow
- SwissProt: P43487 Human
- SwissProt: P34022 Mouse
- Unigene: 24763 Human
see all -
别名
- HTF9A antibody
- RAN binding protein 1 antibody
- Ran specific GTPase activating protein antibody
see all
图片
-
Western blot - Anti-RanBP1 antibody (ab2937)All lanes : Anti-RanBP1 antibody (ab2937) at 1/1000 dilution
Lane 1 : HeLa cell lysate
Lane 2 : Human brain tissue lysate
Lane 3 : NIH-3T3 cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : HRP conjugated anti-rabbit
Developed using the ECL technique.
Predicted band size: 24 kDa
Observed band size: 27 kDa why is the actual band size different from the predicted?
Exposure time: 1 minute
数据表及文件
-
SDS download
-
Datasheet download
文献 (3)
ab2937 被引用在 3 文献中.
- Prpar Mihevc S et al. TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins. Sci Rep 6:33996 (2016). WB, ICC/IF . PubMed: 27665936
- Štalekar M et al. Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport. Neuroscience 293:157-70 (2015). WB, ICC/IF . PubMed: 25743254
- Schulz M et al. Proteomic analysis of peripheral blood mononuclear cells: selective protein processing observed in patients with rheumatoid arthritis. J Proteome Res 6:3752-9 (2007). WB ; Human . PubMed: 17705417